Place of work

Institute of Fundamental Medicine and Biology of  Kazan (Volga Region) Federal University

Position

Director

Academic degree and title

Doctor of Medical Sciences, Professor

Education

Kazan State Medical University (1979-1985), pediatrician

Places of work in the past

Kazan State Medical University

Areas of scientific interest and research

Regenerative medicine, cell-based therapy, gene therapy, translational medicine

Honorary titles and awards

Full Member of the Academy of Sciences of the Republic of Tatarstan

Award Name, Awarding Authority, Date

·         Honorary Diploma of the Ministry of Education and Science of the Republic of Tatarstan, 2015

·         Certificate of Honor from the Ministry of Education and Science of the Republic of Tatarstan, 2015

·         Letter of thanks from the Ministry of Civil Defense and Emergencies of the Republic of Tatarstan, 2015

·         Letter of gratitude from the Ministry of Youth Affairs and Sports of the Republic of Tatarstan, 2015

·         Honorary title "Honored Scientist of the Republic of Tatarstan", March 24, 2018

·         Letter of gratitude from the President of the Republic of Tatarstan, February 26, 2021    

·         Honorary title “Honored Worker of Education of the Russian Federation”, November 12, 2020.

·         Нonorary Diploma of the Ministry of Science and Higher Education of the Russian Federation "For significant contribution to the development of medical education in the Russian Federation", 2024.

Main publications

1.            Teixeira R.B. Improved cognitive, affective and anxiety measures in patients with chronic systemic disorders following structured physical activity / Teixeira R.B., Marins J.C.B., de Sa Junior A.R.,. de Carvahlo C.J, da Silva Moura T. A., Lade C.G., Rizvanov A.A., Kiyasov A.P., Mukhamedyarov M.A., Zefirov A.L., Palotas A., Lima L.M. // Diabetes & Vascular Disease Research I-10

2.            Masgutov R.F. Human adipose-derived stem cells stimulate neuroregeneration / Masgutov R.F., Masgutova G.A., Zhuravleva M.N., Salafutdinov I.I., Mukhametshina R.T., Muhamedshina Y.O., Lima L.M., Reis H.J., Kiyasov A.P., Palotas A., Rizvanov A.A. // Clinical and Experimental Medicine. – 2015.

3.            Islamov R.R. Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule / Islamov R.R.,. Rizvanov A.A, Mukhamedyarov M.A., Salafutdinov I.I., Garanina E.E., Fedotova V.Y., Solovyeva V.V., Mushamedshina Y.O.,. Safiullov Z.Z, Izmailov A.A., Guseva D.S., Zefirov A.L., Kiyasov A.P., A. Palotas // Current Gene Therapy. – 2015. – №15 (2), с. 266-276

4.            Garanina E.E. Construction of recombinant adeno-virus containing picorna-viral 2A-peptide sequence for the co-expression of neuro-protective growth factors in human umbilical cord blood cells / Garanina E.E., Mukhamedshina Y.O.,  Salafutdinov I.I., Kiyasov A.P., Lima L.M., Reis H.J., Palotás A., Islamov R.R., Rizvanov A.A. // Spinal Cord. – 2015. - V.54(6). - p.423-430

5.            Arnst N. Spatial patterns and cell surface clusters in perineuronal nets / Arnst N., Kuznetsova S., Lipachev N., Shaikhutdinov N., Melnikova N., Mavlikeev M., Baltina T.V., Rauvala H, Osin Y.N., Kiyasov A.P., Paveliev M. // Brain Res. 2016.- V.1648. - pp. 214-223. pii: S0006-8993(16)30493-0. doi: 10.1016/j.brainres.2016.07.020.

6.            Ataei A. Genome-Wide Analysis of mRNA Expression in Hu-man Tooth Germ Stem Cells Treated with Pluronic P85 / Ataei A., Solovyeva V.V., Blatt N.L., Salafutdinov I.I., Kiyasov A.P., Rizvanov A.A., Poorebrahim M., Şahin F., Yalvaç M.E. // BioNanoScience. - 2016. - Vol.6, Is.4. - P.392-402.

7.            Burganova, G. Liver cells proliferation and apopto-sis in patients with alcoholic liver disease after au-tologous hematopoietic stem cell transplantation / Burganova G.,  Abdulkhakov S., Gazizov I., Gumerova A., Titiova M., Odintcova A., Kiyasov A.P.// BioNanoScience. - 2016. - Р 1-4.

8.            Shafigullina, A. K. Effect of Adenoviral Transduc-tion of Hepatic Stellate Cells with Adv5-optHGF-RFP on their Phenotype / Shafigullina A.K., Zaikina E.I., Garanina E.E., Sakhapov D.I., Titova A.A., Mavlikeev M.O.,  Rizvanov A.A., Gumerova A.A., Kiassov A.P. // BioNanoScience. - 2016. - Vol. 6. - Р. 1-4.

9.            Quantification of developmental and pathology-related changes in perineuronal nets / Lipachev N., Arnst N., Melnikova A., Kochneva A., Rascheskov A., Mavlikeev M., Rauvala H., Kiyasov A.P., Paveliev M. // Opera Medica et Physiologica. 2017. Т. 3. № 3 (8). С. 9-9_2.

10.         Mavlikeev M. Histopathological Analysis of Skeletal Muscle Biopsy of Patient with Peripheral Arterial Disease before and after Peripheral Blood Stem Cells Intramuscular Injection / Mavlikeev M., Plotnikov M., Maximov A., Murtazin A., Gafiatullina G., Titova A., Gazizov I., DeevR., GumerovaA., Kiyasov A. // BioNanoSci. (2017) 7:186–188. DOI 10.1007/s12668-016-0336-4

11.         Kaligin M.Population dynamics of MafA-positive cells during ontogeny of human pancreas / Kaligin M., Pliushkina A., Titova A., Titova M., Gumerova A, Kiassov A. // BioNanoSci. - 2017. Vol.7, Is.2. - P.352-359 - DOI 10.1007/s12668-016-0369-8

12.         Zaikina E.I. Native and Activated Hepatic Stellate Cells Stimulate Liver Regeneration in Rats After Partial Hepatectomy and 2-Acetylaminofluorene Injection / Zaikina E.I, Shafigullina A.K, Titova A.A. Kiassov A. // BioNanoScience. - 2017. - Vol.7, Is.1. - P.246-250.

13.         Singh A.K Selaginella bryopteris Aqueous Extract Improves Stability and Function of Cryopreserved Human Mesenchymal Stem Cells / A.K Singh, A. Jha, A. Bit, A.P. Kiassov, A.P. Rizvanov, A. Ojha, P. Bhoi, P.K. Patra, A. Kumar, A. Bissoyi // Oxidative Medicine and Cellular Longevity. - 2017. - Vol.2017, Is.. - Art. № 8530656.

14.         Gomzikova M.O. Cytochalasin B-induced membrane vesicles convey angiogenic activity of parental cells / Gomzikova M.O., Zhuravleva M.N., Miftakhova R.R., Arkhipova S.S., Evtugin V.G., Khaiboullina S.F., Kiyasov A.P., Rizvanov A.A., Persson J.L., Mongan N.P., Pestell R.G. // Oncotarget. 2017. Т. 8. № 41. С. 70496-70507.

15.         Kovac M. Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports / Kovac M., Aliev R.O., Litvin Y.A., Zakirova E.Y., Kiyasov A.P., Rizvanov A.A., Rutland C.S. // Frontiers in Veterinary Science. 2017. Т. 4. № OCT. С. 168.

16.         Shafigullina, A. K. Effect of curcumin and gliotox-in on rat liver myofibroblasts culture / Shafigullina A.K., Mijanovich O., Prottoy R.A., Zhurav-leva M.N., Gomzikova M.O., Gumerova A.A., Rizvanov A.A., Kiyasov A.P.  // BioNanoScience. - 2018. - Vol. 8. - Р. 522-536.

17.         Mavlikeev M. Caroli syndrome: a clinical case with detailed histopathological analysis / Mavlikeev M, Titova A, Saitburkhanova R, Abyzova M, Sayfutdinov I, Gizzatullina N, Kotov I, Plaksa I, Isaev A, Abdulkhakov S, Kiyasov A, Deev R. // Clin J Gastroenterol. 2018 Oct 20. doi: 10.1007/s12328-018-0917-6

18.         Kiassov A. Whether Medical Schools in Russia Are Ready to Develop Successfully in the Twenty-first Century / Kiassov A., Gumerova A., Abdulkhakov S., Faizullin R., Mrasov M., Rashitov L., Gaifullina R., Khasanova R.,  Oslopova J. Rizvanov A. // BioNanoScience 2018 8(1), с. 467-472

19.         Kaligin M. Target Cells for Stem Cell Factor in the Adult Islets of Langerhans, Simultaneously Synthesizing Glucagon and Insulin / Kaligin M., Andreeva D., Titova A., Titova M., Gumerova A., Kiyasov A. // BioNanoScience. -2018. - Vol.8, Is.1. - P.296-298. DOI 10.1007/s12668-017-0444-9

20.         Lipachev N. Quantitative changes in perineuronal nets in development and posttraumatic condition / Lipachev N, Arnst N, Melnikova A, Jäälinoja H, Kochneva A, Zhigalov A, Kulesskaya N, Aganov AV, Mavlikeev M, Rauvala H, Kiyasov AP, Paveliev M.J // Mol Histol.-2019.-Vol.50.-Is.3.-P.203-216

21.         Abdulkhakov S.R. Screening Assessment of Renal Function Status in Healthy Smoking Volunteers / Abdulkhakov S.R., Arkhipov E.V., Faizullin R.I., Sidorova I.V., Ibragimova A.A., Gaysina L.R., Oslopova J.V., Pronina E.Ju., Safina D.D., Valeeva I.Kh., Salomatin V.A., Gnuchikh E.V., Arinina E.E., Kiassov A.P. // BioNanoSci.-2019.-Vol.9.-Р.510-514 https://doi.org/10.1007/s12668-019-0602-3

22.         Masgutov, R. Adipose-Derived Mesenchymal Stem Cells Applied in Fibrin Glue Stimulate Peripheral Nerve Regeneration / Masgutov R., Masgutova G., Mullakhmetova A., Zhuravleva M., Shulman A., Rogozhin A., Syromiatnikova V., Andreeva D., Zeinalova A.,. Idrisova K, Allegrucci C., Kiyasov A., Rizvanov A.// Frontiers in Medicine. – 2019. – Vol. 6. – Ar.ID 68. doi: 10.3389/fmed.2019.00068.

23.         Titova A.A. Early ultra- and microstructural alterations in rat pancreas in alloxan-induced diabetes mellitus/ Titova A.A., Mavlikeev M.O., Kaligin M.S., Suleymanova D.M., Chekmaryeva I.A., Kiyasov A.P., Deev R.V  // Ultrastructural Pathology. - 2020. - Vol.44, Is. 1,2. - Р.61-70

24.         Elvira E. Ziganshina. Comparison of the microbiota and inorganic anion content in the saliva of patients with gastroesophageal reflux disease and gastroesophageal reflux disease-free individuals / Elvira E. Ziganshina, Ildar I. Sagitov, Ramilya F. Akhmetova, Gulshat T. Saleeva, Andrey P. Kiassov, Natalya E. Gogoleva, Elena I. Shagimardanova, Ayrat M. Ziganshin // Biomed research internationaL. - 2020. - Vol.2020.  https://doi.org/10.1155/2020/2681791

25.         Pathogenesis, diagnosis, and treatment of hemostatic disorders in covid-19 patients /

Khalirakhmanov A.F., Idrisova K.F., Gajfullina R.F., Zinchenko S.V., Litvinov R.I., Sharafeev A.Z., Kiyasov A.P., Rizvanov A.A. // Acta Naturae. 2021. Т. 13. № 2. С. 79-84

26.         Gatina D.Z. Proangiogenic effect of 2A-peptide based multicistronic recombinant constructs encoding VEGF and FGF2 growth factors / Gatina D.Z., Garanina E.E., Zhuravleva M.N., Synbulatova G.E., Mullakhmetova A.F.,  Solovyeva V.V., Kiyasov A.P., Rutland C.S.,  Rizvanov A.A., Salafutdinov I.I. // International Journal of Molecular Sciences, 2021, 22(11), 5922

27.         Salafutdinov I.I. Influence of Recombinant Codon-Optimized Plasmid DNA Encoding VEGF and FGF2 on Co-Induction of Angiogenesis. Salafutdinov I.I., Gazizov I.M., Gatina D.K., Mullin R.I., Bogov A.A., Islamov R.R., Kiassov A.P., Masgutov R.F., Rizvanov A.A. Cells 2021, 10 (2)

28.         Khalirakhmanov A.F. Pathogenesis, Diagnosis, and Treatment of Hemostatic Disorders in COVID-19 Patients. Khalirakhmanov A.F., Idrisova K.F., Gaifullina R.F., Zinchenko S.V., Litvinov R.I., Sharafee, A.Z., Kiyasov A.P., Rizvanov A.A.  Acta Naturae 2021, 13 (2), 79 – 84. DOI: 10.32607/actanaturae.11182

29.         Kaligin M. Dividing Cells in Islets of Langerhans Can produce Glucagon / Kaligin M., Valijonov Kh., Pliushkina A., Andreeva D., Titova A. Titova M., UrsanR., Kiyasov A. // BioNanoScience 2022, 12: 1388-93. 10.1007/s12668-022-00989-9.

30.         Kitaeva K. Stem cells, fitness, and aging / Kitaeva K., Kiyasov A., Rizvanov A., Rutland C., Solovyeva V.// Aging. From fundamental biology to societal impact. Ed: P.J. Oliveira, J.O. Malva. New York: Academic Press. 2023 385-405

31.         Kitaeva, A. Kiyasov, A. Rizvanov, C. Rutland, V. Solovyeva // In: Aging: From Fundamental Biology to Societal Impact. Elsevier – 2023. –  P. 385-405. ISBN: 978-0-12-823761-8. DOI: https://doi.org/10.1016/B978-0-12-823761-8.00007-0.

32.         Chernova O. N. Structural and ultrastructural changes in the skeletal muscles of dysferlin-deficient mice during postnatal ontogenesis / Chernova O. N., Chekmareva I. A., Mavlikeev M. O., Yakovlev I. A., Kiyasov A. P., Deev R.V. // Ultrastructural Pathology 2022, 46:4, 359-67, DOI: 10.1080/01913123.2022.2105464

33.         Lipachev N. Postnatal development of the microstructure of cortical GABAergic synapses and perineuronal nets requires sensory input / Lipachev N., Melnikova A., Fedosimova S., Arnst N., Kochneva A., Shaikhutdinov N., Dvoeglazova A., Titova A., Mavlikeev M., Aganov A., Osin Y., Kiyasov A., Paveliev M.// Neuroscience Research 2022, 182: 32-40. https://doi.org/10.1016/j.neures.2022.06.005.

34.         Bilyalov A.I. Post-traumatic histogenesis of auricle tissues of spiny mouse Acomys / Bilyalov A.I., Filimoshina D., Titova A.A., Shagimardanova E.I., Gusev O.A., Kiyasov A.P. // New day in Medicine 2022; 3(41): 382-5

35.         Bilyalov A, Nikolaev S, Danishevich A, Khatkov I, Makhmudov K, Isakova Z, Bakirov N, Omurbaev E, Osipova A, Ramaldanov R, et al. The Spectrum of Germline Nucleotide Variants in Gastric Cancer Patients in the Kyrgyz Republic. Current Issues in Molecular Biology. 2023; 45(8):6383-6394. https://doi.org/10.3390/cimb45080403

36.         Combination of Histological and Transcriptomic Approaches for Annotation of Cell Types in Non-Model Organisms by Example of Spiny Mice Acomys cahirinus. N.S., Filatov, N. S., A.I., Bilyalov, A. I., G.R., Gazizova, Guzel R., ... O.A., Gusev, Oleg A., O.S., Kozlova, Olga S. Russian Journal of Genetics, 2024

37.         Non-classical animal models for studying adrenal diseases: advantages, limitations, and implications for research A.A., Bilyalova, Alina A., A.I., Bilyalov, A. I., N.S., Filatov, N. S., ... M.V., Vorontsova, Maria V., O.A., Gusev, Oleg A. Laboratory Animal Research, 2024

38.         Distinct Hemostasis and Blood Composition in Spiny Mouse Acomys cahirinus N.S., Filatov, N. S., R.R., Khismatullin, Rafael R., A.I., Bilyalov, A. I., ... R.I., Litvinov, R. I., O.A., Gusev, Oleg A. International Journal of Molecular Sciences, 2024